A cell culture biomaterial supplement consisting
of full native human ECM (Extracellular Matrix),
useful for in vitro 4D bioprinting
and cell culturing as well as clinical translational studies

HumaTein™
about HumaTein™
What is HumaTein™?

HumaTein™ is a human cell derived whole Extracellular Matrix(ECM), comprised of more than 300 proteins and associated cytokines.
HumaTein™ opens new possibilities for regeneration researches and relative studies.

Applications

2D/3D Culture

Wound Healing

Anti-Aging

HumaTein™ Matrix is an ideal coating material for feeder layer free induced pluripotent stem cell (iPSC) culture. Xeno free and human cell derived Huma Tein is optimized for organoid research.

  • Cancer Research
  • Stem Cell Research
  • Drug Discovery
  • Tissue Engineering & Regenerative Medicine
Characteristics

Native whole ECM

Manufacturing processes do not include harsh chemical processing. HumaTein™ preserves whole ECM components.

Organ specific

With ROKIT’s cell sheet technologies, HumaTein™ provides organ specific stiffness controlled environment.

Regeneration

HumaTein™ is applicable for regeneration studies.

In vivo like
environment

Human primary cell derived HumaTein™ provides the most in-vivo like environment to cells, and this enables translational studies.

Custom ECM

With your own cell choice, you can order customized HumaTein™ Special Matrix.

Easy Control

HumaTein™ is not sensitive to temperature changes. It's users friendly texture type.
about HumaTein™
How to use?
Humatein™ Mixture
Humatein™ Hydrogel
Fibroblast Mesenchymal Stem Cells
(primary cells)
Patient biopsy derived Cells Your Lab Choice Cells
Humatein™ Essential
Humatein™ MSC
Humatein™ Special Matrix
Cell Culture Process
Organoid
iPSC Culture
What ROKIT Provides
What ROKIT Supports
Why HumaTein
Regeneration potential of HumaTein

Rapid dermal regeneration & re-epithelialization (9cm x 9cm) within 4 weeks in porcine model

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about HumaTein™
How HumaTein™ is made?

HumaTein™ is Isolated from specific native stiffness matching micro-environment grown human cells. HumaTein™ composition is optimized for a target cell type growth and proliferation in a native-like environment.

Cytokine ELISA Array Analysis Comparison

Humatein™ is clinically applicable

99%

Contains 506 essential human Cytokines (SMAD9)

Xenogetic ECM is NOT clinically applicable

73%

Lacks about 27% of cytokines Found in human body

3D Models
Control
Humatein MSC Matrix

A) Phase contrast images of iPSC spheroid.
iPSCs are cultured with MSC-derived HumaTein for a day.

B) Analysis of iPSC spheroid size

Colon organoid using Humatein™ (0.2%)

Actin
Ki-67
DAPI

· Colon organoid with HumaTein™ Essential Matrix (1㎎/㎖)
· Similar size and structure to xenogetic source colon organoid

HumaTein™ Lines

HumaTein™ Lines

HumaTein™ Essential Matrix 50mg

HumaTein™ Essential Matrix 100mg

HumaTein™ Essential Matrix 100mg*5

HumaTein™ MSC Matrix 30mg

HumaTein™ MSC Matrix 60mg

HumaTein™ SPECIAL ORDER 30mg

Catalog#

HT-MD-001-A

HT-MD-001-B

HT-MD-001-C

HT-MD-12

HT-MD-13

HT-CO-01

※ HumaTein™ is provided in mixture and hydrogel types.

Xeno Free HumaTein™ is a next generation material for implantable organoid and clinical translation.
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