Posted in SCI-class international journals for verifying the efficacy of renal failure treatment patches, renal fibrosis in renal failure models, and reduced tubal abnormalities.
The efficacy of the developed renal failure treatment patch has been verified through preclinical studies. The results of the study were adopted as a cover paper in December last year in the leading journal Tissue Engineering Part C as a paper titled “Improvement of renal fibrosis of self-entum patches printed on 3D bio-printers.
This study was conducted in collaboration with a research team from the Department of Renal Internal Medicine and Pathology at Seoul National University and the Department of Renal and Pancreatic Transplantation at Asan Hospital. A 3D printing-based treatment patch was implanted into an animal model of kidney failure to confirm the effect of reducing renal fibrosis and tubal abnormalities, which are major symptoms of kidney failure. In addition, the research team found that treatment patches in damaged kidneys regulate gene expression and help regenerative treatment through single-cell sequencing.
Link to the paper : 논문_2022_KIDNEY_Three-dimensional bio-printed autologous omentum patch ameliorates unilateral ureteral obstruction induced renal fibrosis (1)