Built-in Cell Incubator
CO₂ level control
Clean Chamber
Sterilization
Particle control system
Auto Bed Leveling
& Nozzle End Alignment
Ultrasonic sensor
about Dr. INVIVO 4D6
INEVITABLE AGING IS OVER
Dr. INVIVO 4D6 guarantees optimal cell growth environments.
- HOME FOR CELLS
- COMPLEX TISSUES BUT EASY FABRICATION
MODULAR Printheads
1 interchangeable dispenser
+ 5 rotary biodispersers
VISUALIZATION
Optical microscope
Multi Platform Printing Bed
Well plates, culture dish
Dr. INVIVO 4D6’s Competitiveness
Next-Generation bioprinting
- Biofabricator
- Incubator
- LIQUID handler
- Sterilizer
- Smart UI
IMPORTANT BIOLOGICAL PRINTING PARAMETERS
Temperature
Cellular functions are highly responsive to temperature which can also affect cell viability.
CO₂
CO₂ gas changes pH in the medium. In the improper pH conditions, cells stop growing and lose viability and it may produce morphological changes of cells.
Humidity
Low humidity causes evaporation of water from the media. Evaporation leaves too-high concentrations of salts, minerals, etc., resulting in toxicity and cell death.
Sterilization
Preventing contamination is the key to apply the printed tissue in vivo.
Replicating the temperature, CO₂ and humidity with in vivo conditions is important to replicate tissues and organs.
Why Dr. INVIVO 4D6
Dr. INVIVO 4D6
A next-generation bioprinting technology should be ready for the most complex challenges in human tissue fabrication and applications. Stepping up from simply laying cells out in a 3-dimensional space, Dr. INVIVO 4D6, with the built-in cell incubator and liquid handling functions, allows the researcher to meet the real needs of keeping cells functional while upgrading researchers’ work to high-throughput usage.
Chamber Temperature Control
(4~ 40 ℃)
Fabricates with diverse types of hydrogels
Max 6 Modular Printheads
Fabricates complex tissue structures with six different cell types and/or materials
Sterile Chamber
Creates implantable devices in an environment compliant with medical device standards
Cell Incubator
(Temperature/Humidity/CO₂)
· Supports higher cell viability both during and after the printing process
Well-Plate Printing
(up to 384 wells)
· Creates an assay composed of organoids that can be used for drug efficacy and toxicity testing
20X Built-In Scope
Allows for quality evaluation of scaffolds
Standard
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Printing Bed
O
-
Embedded Incubator
O
-
Syringe Dispenser
O
-
Filament Extruder
O
-
Hot-melting Dispenser
—
Upgrade
-
Printing Bed
O
-
Embedded Incubator
O
-
Syringe Dispenser
O
-
Filament Extruder
O
-
Hot-melting Dispenser
—
Premium
-
Printing Bed
O
-
Embedded Incubator
O
-
Syringe Dispenser
O
-
Filament Extruder
O
-
Hot-melting Dispenser
O
