Built-in Cell Incubator CO₂ level control

Clean Chamber Sterilization Particle control system

Auto Bed Leveling & Nozzle End Alignment Ultrasonic sensor

about Dr. INVIVO 4D6
INEVITABLE AGING IS OVER

Dr. INVIVO 4D6 guarantees optimal cell growth environments.

  • HOME FOR CELLS
  • COMPLEX TISSUES BUT EASY FABRICATION

MODULAR Printheads 1 interchangeable dispenser + 5 rotary biodispersers

VISUALIZATION Optical microscope

Multi Platform Printing Bed Well plates, culture dish

Dr. INVIVO 4D6’s Competitiveness
Next-Generation bioprinting
  • Biofabricator
  • Incubator
  • LIQUID handler
  • Sterilizer
  • Smart UI
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IMPORTANT BIOLOGICAL PRINTING PARAMETERS

Temperature
Cellular functions are highly responsive to temperature which can also affect cell viability.

CO₂
CO₂ gas changes pH in the medium. In the improper pH conditions, cells stop growing and lose viability and it may produce morphological changes of cells.

Humidity
Low humidity causes evaporation of water from the media. Evaporation leaves too-high concentrations of salts, minerals, etc., resulting in toxicity and cell death.

Sterilization
Preventing contamination is the key to apply the printed tissue in vivo.

Replicating the temperature, CO₂ and humidity with in vivo conditions is important to replicate tissues and organs.

Why Dr. INVIVO 4D6
Dr. INVIVO 4D6

A next-generation bioprinting technology should be ready for the most complex challenges in human tissue fabrication and applications. Stepping up from simply laying cells out in a 3-dimensional space, Dr. INVIVO 4D6, with the built-in cell incubator and liquid handling functions, allows the researcher to meet the real needs of keeping cells functional while upgrading researchers’ work to high-throughput usage.

Chamber Temperature Control (4~ 40 ℃)

Fabricates with diverse types of hydrogels

Max 6 Modular Printheads

Fabricates complex tissue structures with six different cell types and/or materials

Sterile Chamber

Creates implantable devices in an environment compliant with medical device standards
4d6_2

Cell Incubator (Temperature/Humidity/CO₂)

· Supports higher cell viability both during and after the printing process

Well-Plate Printing (up to 384 wells)

· Creates an assay composed of organoids that can be used for drug efficacy and toxicity testing

20X Built-In Scope

Allows for quality evaluation of scaffolds

Standard

  • Printing Bed

    O

  • Embedded Incubator

    O

  • Syringe Dispenser

    O

  • Filament Extruder

    O

  • Hot-melting Dispenser

Upgrade

  • Printing Bed

    O

  • Embedded Incubator

    O

  • Syringe Dispenser

    O

  • Filament Extruder

    O

  • Hot-melting Dispenser

Premium

  • Printing Bed

    O

  • Embedded Incubator

    O

  • Syringe Dispenser

    O

  • Filament Extruder

    O

  • Hot-melting Dispenser

    O

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