ROKIT Healthcare Organ Regeneration Platform seeks a convergence of five key factors essential for regeneration of functional human tissues and organs.

  • ECM
4D Bioptinting
Evolution from 2D Cell Culture to 4D Tissue Analogs

4D bioprinting is the automated and computer-aided layer-by-layer deposition of bio-materials, cells, stem cell growth factors, and biocompatible polymers for manufacturing of functional human tissues or organs.

4D bioprinting with bio-scaffold, stem cell and bio-ink is one of the most promising solutions currently explored for regenerative medicine as an alternative to organ transplantation.

our services
4D Bioprinting the Healthcare Solution

4D bioprinting has been used widely in many different field of studies. Currently, many researchers incorporated 4D bioprinting into their researches. Now, it can replace what’s been done manually, but its possibility is infinite and future with 4D bioprinting is bright. 

Stem cell Therapy
With the ability to customize scaffold shapes and cell seeding patterns, combined with the ability to use pluriopotent stem cells, 4D bioprinting opens whole new avenues in autologous, patient-specific cell therapy development.
Skin Regeneration
Using a 4D bioprinter and components of dermal matrics, it is possible to create artificial human skin. Human skin equivalents are currently used in topical drug screening and cosmetic toxicity tests, offering promising alternatives to animal testing.
4D bioprinting helps to replicate the naturally occurring architectural complexities in craniofacial tissues and to develop novel scaffold biomaterials for bone and oral tissue regeneration.
Polymer Development
Polymers are macromolecules composed of many subunits which form linear, branched, or crosslinked structures. They allow controlled degradation and facilitate the attachment of anchorage-dependent cells by providing a supportive matrix for cell survival and proliferation.
4D bioprinting provides the ability to print bone substitute materials with a controlled chemistry, shape, geometry, porosity, and topography, thus allowing printing of personalized bone grafts specific to the patient’s clinical condition. 4D bioprinting fabrication approaches of bone grafts may revolutionize the way clinicians currently treat bone defects.
4D bioprinting has the potential to revolutionize pharmaceutical manufacturing by replacing mass production with a delivery of customized pill formulations via pharmacies, which makes possible cost reduction through reduced margins and quality improves through personalized therapy provision.

Our Dr. INVIVO users worldwide have been at the frontline of exploring the limitless possibilities of tissue, material, and pharmaceutical engineering with 4D bioprinting, with an ultimate goal of moving its power to the clinic:

  • Artificial human skin development
  • Implantable synthetic bone development
  • Pancreatic cancer treatment research
  • Implantable Heart Patch Regeneration
  • Bio-ink (hydrogel) development
  • Bio-material printability testing research
  • Biomechanical studies on 4D printable materials
  • Alternative plant-derived bio-ink development
  • In vitro drug screening for cancer treatment
  • Drug delivery system study
  • Ear cartilage regeneration
  • Smart bio-sensor with thermo-sensitive materials